Myoglobinuria

Myoglobinuria
Myoglobinuria
Classification and external resources

Urine from a person with rhabdomyolysis showing the characteristic brown discoloration as a result of myoglobinuria
ICD-10 R82.1
ICD-9 791.3
DiseasesDB 23059
eMedicine ped/1535
MeSH D009212
Model of helical domains in myoglobin.

Myoglobinuria is the presence of myoglobin in the urine, usually associated with rhabdomyolysis or muscle destruction. Myoglobin is present in muscle cells as a reserve of oxygen.

Contents

Causes

Trauma, vascular problems, venoms, certain drugs and other situations can destroy or damage the muscle, releasing myoglobin to the circulation and thus to the kidneys.

Under ideal situations myoglobin will be filtered and excreted with the urine, but if too much myoglobin is released into the circulation or in case of renal problems, it can occlude the renal filtration system leading to acute tubular necrosis and acute renal insufficiency.

Other causes of myoglobinuria include:

Diagnosis

After centrifuging, the serum of myoglobinuria is clear, where the serum of hemoglobinuria after centrifuge is pink.[citation needed]

External links

  • Overview on the Neuromuscular disease center website.

References



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Look at other dictionaries:

  • myoglobinuria — noun The presence of myoglobin in the urine, usually associated with rhabdomyolysis or muscle destruction …   Wiktionary

  • myoglobinuria — Excretion of myoglobin in the urine; results from muscle degeneration, which releases myoglobin into the blood; occurs in certain types of trauma (crush syndrome), advanced or protracted ischemia of muscle, or as a …   Medical dictionary

  • myoglobinuria — n. presence of myohemoglobin in the urine (Medicine) …   English contemporary dictionary

  • myoglobinuria — my·o·glo·bin·uria …   English syllables

  • myoglobinuria — n.; see myohaemoglobinuria …   The new mediacal dictionary

  • myoglobinuria — noun the presence of myoglobin in the urine • Hypernyms: ↑symptom * * * ˌmīəˌglōbəˈn(y)u̇rēə noun ( s) Etymology: New Latin, from International Scientific Vocabulary …   Useful english dictionary

  • familial myoglobinuria — idiopathic myoglobinuria Meyer Betz disease …   Medical dictionary

  • paralytic myoglobinuria — azoturia (def. 2) …   Medical dictionary

  • spontaneous myoglobinuria — Meyer Betz disease …   Medical dictionary

  • миоглобинурия — (myoglobinuria; миоглобин + греч. uron моча) наличие в моче миоглобина; наблюдаются при патологическом распаде мышечного белка …   Большой медицинский словарь

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