Miocamycin

Miocamycin: Miocamycin

Systematic (IUPAC) name

(2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4S,5R,6S,7R,9R,10R,11E,13E,16R)-10-(acetyloxy)-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-4-propoxy-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-3-propoxyoxan-4-yl acetate

Clinical data

AHFS/Drugs.com International Drug Names

Pregnancy cat. ?

Legal status ?

Identifiers

CAS number 55881-07-7

ATC code J01FA11

PubChem CID 6475694

ChemSpider 16735908^Y

ChEMBL CHEMBL1091024^Y

Chemical data

Formula C₄₅H₇₅N O₁₅

Mol. mass 870.075 g/mol

SMILES eMolecules & PubChem

InChI

InChI=1S/C45H71NO17/c1-13-34(50)59-33-23-36(52)55-26(4)18-16-15-17-19-32(58-29(7)48)25(3)22-31(20-21-47)41(42(33)54-12)62-44-39(53)38(46(10)11)40(27(5)57-44)61-37-24-45(9,63-30(8)49)43(28(6)56-37)60-35(51)14-2/h15-17,19,21,25-28,31-33,37-44,53H,13-14,18,20,22-24H2,1-12H3/b16-15+,19-17+/t25-,26-,27-,28+,31+,32+,33-,37+,38-,39-,40-,41+,42+,43+,44+,45-/m1/s1^Y
Key:GQNZGCARKRHPOH-RQIKCTSVSA-N^Y

Physical data

Melt. point 220 °C (428 °F)

Solubility in water Slightly soluble in water; Soluble in methanol, acetone and chloroform. mg/mL (20 °C)

Y(what is this?) (verify)

Miocamycin is a macrolide antibiotic.

v · d · eAntibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ)

30S

Aminoglycosides
(initiation inhibitors)

-mycin (Streptomyces)

Streptomycin^#

Neomycin^# (Framycetin, Paromomycin, Ribostamycin)

Kanamycin^# (Amikacin, Arbekacin, Bekanamycin, Dibekacin, Tobramycin)

Spectinomycin^# • Hygromycin B
Paromomycin

-micin (Micromonospora)

Gentamicin^# (Netilmicin, Sisomicin, Isepamicin)
Verdamicin
Astromicin

Tetracycline antibiotics
(tRNA binding)

Tetracyclines

Doxycycline^# •Chlortetracycline • Clomocycline • Demeclocycline • Lymecycline • Meclocycline • Metacycline • Minocycline • Oxytetracycline • Penimepicycline • Rolitetracycline • Tetracycline

Glycylcyclines

Tigecycline

50S

Oxazolidinone
(initiation inhibitors)

Linezolid • Torezolid • Eperezolid • Posizolid • Radezolid

Peptidyl transferase

Amphenicols

Chloramphenicol^# • Azidamfenicol • Thiamphenicol • Florfenicol

Pleuromutilins

Retapamulin • Tiamulin • Valnemulin

MLS (transpeptidation/translocation)

Macrolides

Erythromycin^# • Azithromycin^# • Spiramycin • Midecamycin • Oleandomycin • Roxithromycin • Josamycin • Troleandomycin • Clarithromycin • Miocamycin • Rokitamycin • Dirithromycin • Flurithromycin • Ketolide (Telithromycin, Cethromycin, Solithromycin)

Lincosamides

Clindamycin^# • Lincomycin

Streptogramins

Pristinamycin • Quinupristin/dalfopristin • Virginiamycin

EF-G

Steroid antibacterials

Fusidic acid

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)

This systemic antibacterial-related article is a stub. You can help Wikipedia by expanding it.

Academic Dictionaries and Encyclopedias

Miocamycin

Look at other dictionaries:

Share the article and excerpts


Systematic (IUPAC) name
(2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4S,5R,6S,7R,9R,10R,11E,13E,16R)-10-(acetyloxy)-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-4-propoxy-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-3-propoxyoxan-4-yl acetate
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	55881-07-7
ATC code	J01FA11
PubChem	CID 6475694
ChemSpider	16735908^Y
ChEMBL	CHEMBL1091024^Y
Chemical data
Formula	C₄₅H₇₅N O₁₅
Mol. mass	870.075 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C45H71NO17/c1-13-34(50)59-33-23-36(52)55-26(4)18-16-15-17-19-32(58-29(7)48)25(3)22-31(20-21-47)41(42(33)54-12)62-44-39(53)38(46(10)11)40(27(5)57-44)61-37-24-45(9,63-30(8)49)43(28(6)56-37)60-35(51)14-2/h15-17,19,21,25-28,31-33,37-44,53H,13-14,18,20,22-24H2,1-12H3/b16-15+,19-17+/t25-,26-,27-,28+,31+,32+,33-,37+,38-,39-,40-,41+,42+,43+,44+,45-/m1/s1^Y Key:GQNZGCARKRHPOH-RQIKCTSVSA-N^Y
Physical data
Melt. point	220 °C (428 °F)
Solubility in water	Slightly soluble in water; Soluble in methanol, acetone and chloroform. mg/mL (20 °C)
Y(what is this?) (verify)

Academic Dictionaries and Encyclopedias

Wikipedia

Miocamycin

Look at other dictionaries:

Share the article and excerpts

Direct link