Yersinia enterocolitica

Yersinia enterocolitica

Taxobox
color = lightgrey
name = "Yersinia enterocolitica"



image_width = 240px
image_caption = "Yersinia enterocolitica" colonies growing on XLD agar plates.
regnum = Bacteria
phylum = Proteobacteria
classis = Gamma Proteobacteria
ordo = Enterobacteriales
familia = Enterobacteriaceae
genus = "Yersinia"
species = "Y. enterocolitica"
binomial = "Yersinia enterocolitica"
binomial_authority = (Schleifstein & Coleman 1939)

"Yersinia enterocolitica" is a species of gram-negative coccobacillus-shaped bacterium, belonging to the family Enterobacteriaceae. Primarily a zoonotic disease (cattle, deer, pigs, and birds), animals that recover frequently become asymptomatic carriers of the disease.cite book | author = Collins FM | title = Pasteurella, Yersinia, and Francisella. "In:" Barron's Medical Microbiology "(Barron S "et al", eds.)| edition = 4th ed. | publisher = Univ of Texas Medical Branch | year = 1996 | id = [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mmed.section.1621 (via NCBI Bookshelf)] ISBN 0-9631172-1-1 ]

Pathogenesis

Acute infections

Acute "Y. enterocolitica" infections produce severe diarrhea in humans, along with Peyer's patch necrosis, chronic lymphadenopathy, and hepatic or splenic abscesses. Additional symptoms may include entero-colitis, fever, mesenteric adenitis, erythema nodosum and acute terminal ileitis, which may be confused with appendicitis or Crohn's disease. Because "Yersinia" is a siderophilic (iron-loving) bacteria, those with hereditary hemochromatosis (a disease resulting in high body iron levels) are more susceptible to infection with "Yersinia" (and other siderophilic bacteria). See yersiniosis for further details.

Treatment

Treatment of "Y. enterocolitica" infections often requires aggressive antibiotic therapy, typically involving ciprofloxacin, chloramphenicol, ampicillin, and polymyxin. However, some gastoenterologists, especially in Scandinavia, would say that antibiotic treatment should be initiated only when the patient has significant and persisting symptoms of gastroenteritis.

Long-term effects

"Y. enterocolitica" infections are sometimes followed by chronic inflammatory diseases such as arthritis.cite book | author = Ryan KJ; Ray CG (editors) | title = Sherris Medical Microbiology | edition = 4th ed. | publisher = McGraw Hill | year = 2004 | id = ISBN 0-8385-8529-9 ]

"Y. enterocolitica" seems to be associated with autoimmune Graves-Basedow thyroiditis. cite journal | author=Benvenga S, Santarpia L, Trimarchi F, Guarneri F | title=Human Thyroid Autoantigens and Proteins of "Yersinia" and "Borrelia" Share Amino Acid Sequence Homology That Includes Binding Motifs to HLA-DR Molecules and T-Cell Receptor | journal=Thyroid | year=2006 | pages=225–236 | volume=16 | issue=3 | pmid=16571084 | doi=10.1089/thy.2006.16.225 ] Whilst indirect evidence exists, direct causative evidence is limited, cite journal | author = Tomer Y, Davies T | title = Infection, thyroid disease, and autoimmunity | journal = Endocr Rev | volume = 14 | issue = 1 | pages = 107–20 | year = 1993 | pmid = 8491150 | url=http://edrv.endojournals.org/cgi/reprint/14/1/107.pdf | format=PDF | doi = 10.1210/er.14.1.107] and "Y. enterocolitica" is probably not a major cause of this disease, but may contribute to the development of thyroid autoimmunity arising for other reasons in genetically susceptible individuals. [cite journal | author = Toivanen P, Toivanen A | title = Does Yersinia induce autoimmunity? | journal = Int Arch Allergy Immunol | volume = 104 | issue = 2 | pages = 107–11 | year = 1994 | pmid = 8199453] It has also been suggested that "Y. enterocolitica" infection is not the cause of auto-immune thyroid disease, but rather is only an associated condition; with both having a shared inherited susceptibility. [cite journal | author = Strieder T, Wenzel B, Prummel M, Tijssen J, Wiersinga W | title = Increased prevalence of antibodies to enteropathogenic Yersinia enterocolitica virulence proteins in relatives of patients with autoimmune thyroid disease | journal = Clin Exp Immunol | volume = 132 | issue = 2 | pages = 278–82 | year = 2003 | pmid = 12699417 | doi = 10.1046/j.1365-2249.2003.02139.x] More recently the role for "Y. enterocolitica" has been disputed. [cite journal | author = Hansen P, Wenzel B, Brix T, Hegedüs L | title = Yersinia enterocolitica infection does not confer an increased risk of thyroid antibodies: evidence from a Danish twin study | journal = Clin Exp Immunol | volume = 146 | issue = 1 | pages = 32–8 | year = 2006 | pmid = 16968395 | doi = 10.1111/j.1365-2249.2006.03183.x]

External links

* Genome information is available at the [http://www.ericbrc.org NIAID Enteropathogen Resource Integration Center (ERIC)]

Footnotes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Yersinia enterocolitica — Yersinia enterocolitica …   Wikipédia en Français

  • Yersinia enterocolitica — auf Blutagar Systematik Abteilung: Proteobacteria …   Deutsch Wikipedia

  • Yersinia enterocolitica — Yersinia består af 9 nærtbeslægtede bakteriearter, hvor Yersinia enterocolitica er skyld i fødevarebåren sygdom hos mennesker. Yersinia vokser ved temperaturer på 0 40 grader og vokser derfor fint selv i køleskabet. Yersinia er vidt udbredt i… …   Danske encyklopædi

  • Yersinia enterocolitica — Yersinia enterocolitica …   Wikipédia en Français

  • Yersinia enterocolitica — A bacterium that causes an infectious disease called yersiniosis. Yersinia enterocolitica is a member of the Yersinia family of bacteria. Common symptoms of yersiniosis in children (who most often contract the disease) are fever, abdominal pain,… …   Medical dictionary

  • Yersinia enterocolitica — Este artículo o sección necesita referencias que aparezcan en una publicación acreditada, como revistas especializadas, monografías, prensa diaria o páginas de Internet fidedignas. Puedes añadirlas así o avisar …   Wikipedia Español

  • Yersinia enterocolitica — бактерия рода Yersinia, подвижная, не образующая спор и капсул; культивируется на обычных питательных средах; возбудитель иерсиниоза …   Большой медицинский словарь

  • Yersinia — Yersinia …   Wikipédia en Français

  • Yersinia — pestis Systematik Domäne: Bakterien Abteilung …   Deutsch Wikipedia

  • Yersinia pestis — A scanning electron microscope micrograph depicting a mass of Yersinia pestis bacteria. Scientific classification Domain …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”