Meptazinol

Meptazinol
Meptazinol
Systematic (IUPAC) name
(RS)-3-(3-ethyl-1-methylazepan-3-yl)phenol
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status POM (UK)
Dependence liability Low
Routes Oral, IM, IV
Pharmacokinetic data
Metabolism The peak analgesic effect is seen within 30–60 minutes and lasts about 3–4 hours.
Half-life Half-Life (1.4–4 hours).
Excretion The drug is rapidly metabolised to the glucuronide, and mostly excreted in the urine.
Identifiers
CAS number 54340-58-8 YesY
ATC code N02AX05
PubChem CID 41049
ChemSpider 37469 YesY
UNII 18Y7S5JKZD N
KEGG D08182 YesY
ChEMBL CHEMBL314437 YesY
Chemical data
Formula C15H23NO 
Mol. mass 233.34922 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Meptazinol (trade name Meptid) is an opioid analgesic for use with moderate to severe pain, most commonly used to treat pain in obstetrics (childbirth). A partial µ-opioid receptor agonist, its mixed agonist/antagonist activity affords it a lower risk of dependence and abuse than full µ agonists like morphine. Meptazinol exhibits not only a short onset of action, but also a shorter duration of action relative to other opioids such as morphine, pentazocine, or buprenorphine.[1]

References

  1. ^ Holmes B, Ward A. "Meptazinol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy." Drugs. 1985 Oct; 30(4):285-312. PMID 2998723

External links

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M: CNS

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noco(m/d/e/h/v/s)/cong/tumr, sysi/epon, injr

proc, drug(N1A/2AB/C/3/4/7A/B/C/D)


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