DNAJB4

DnaJ (Hsp40) homolog, subfamily B, member 4
Identifiers
Symbols	DNAJB4; DNAJW; DjB4; HLJ1
External IDs	OMIM: 611327 MGI: 1914285 HomoloGene: 100610 GeneCards: DNAJB4 Gene
Gene Ontology Molecular function • heat shock protein binding • unfolded protein binding Cellular component • cytoplasm • plasma membrane Biological process • protein folding • response to unfolded protein • response to heat Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	11080	67035
Ensembl	ENSG00000162616	ENSMUSG00000028035
UniProt	Q9UDY4	Q9D832
RefSeq (mRNA)	NM_007034	NM_025926
RefSeq (protein)	NP_008965	NP_080202
Location (UCSC)	Chr 1: 78.44 – 78.48 Mb	Chr 3: 151.84 – 151.87 Mb
PubMed search	[1]	[2]

DnaJ homolog subfamily B member 4 is a protein that in humans is encoded by the DNAJB4 gene.^[1][2][3]

References

1. ^ Hoe KL, Won M, Chung KS, Jang YJ, Lee SB, Kim DU, Lee JW, Yun JH, Yoo HS (Apr 1998). "Isolation of a new member of DnaJ-like heat shock protein 40 (Hsp40) from human liver". Biochim Biophys Acta 1383 (1): 4–8. PMID 9546042. 
2. ^ Ohtsuka K, Hata M (Jan 2001). "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature". Cell Stress Chaperones 5 (2): 98–112. doi:10.1379/1466-1268(2000)005<0098:MHDHCO>2.0.CO;2. ISSN 1466-1268. PMC 312896. PMID 11147971. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=312896. 
3. ^ "Entrez Gene: DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11080. 

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. 
• Borges JC, Fischer H, Craievich AF, Ramos CH (2005). "Low resolution structural study of two human HSP40 chaperones in solution. DJA1 from subfamily A and DJB4 from subfamily B have different quaternary structures". J. Biol. Chem. 280 (14): 13671–81. doi:10.1074/jbc.M408349200. PMID 15661747. 
• Wang CC, Tsai MF, Hong TM, et al. (2005). "The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion". Oncogene 24 (25): 4081–93. doi:10.1038/sj.onc.1208573. PMID 15782117. 
• Ancevska-Taneva N, Onoprishvili I, Andria ML, et al. (2006). "A member of the heat shock protein 40 family, hlj1, binds to the carboxyl tail of the human mu opioid receptor". Brain Res. 1081 (1): 28–33. doi:10.1016/j.brainres.2006.01.125. PMID 16542645. 
• Tsai MF, Wang CC, Chang GC, et al. (2006). "A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma". J. Natl. Cancer Inst. 98 (12): 825–38. doi:10.1093/jnci/djj229. PMID 16788156.